Toxicity of A1
I. Physiological function
- Several biological functions for A1 have been suggested from indirect evidence but A1 has not been proven essential for animals.
II. Dietary sources
- A1 cooking utensils and beverage cans
- Ingested soil
- Plants grown in wet, low-oxygen soil take up increased amounts of Al
III. Toxicity of A1
- Chronic A1 excess results in secondary P deficiency
- Reduced P absorption and reduced serum P
- Lower bone ash content
- Disturbances in carbohydrate and P metabolism (reduced ATP: ADP ratio)
- Reduced working capacity
- High A1 content of forage may contribute to hypomagnesemic tetany
- Involved in Alzheimer disease?
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